Absence of Y chromosome in human placental site trophoblastic tumor
نویسندگان
چکیده
منابع مشابه
Sonographic characteristics of placental site trophoblastic tumor.
OBJECTIVE To investigate clinical features and ultrasound findings in cases of placental site trophoblastic tumor (PSTT). METHODS Fourteen cases of PSTT treated at our institution between May 2004 and October 2010 were identified and the clinical features and findings on transvaginal sonography (TVS) were investigated. Pathological confirmation of PSTT was obtained in all cases. RESULTS The...
متن کاملA Rare Gestational Trophoblastic Disease: Placental Site Trophoblastic Tumor
Placental site trophoblastic tumor (PSTT) is a highly rare form of gestational trophoblastic diseases that arise from intermediate trophoblastic cells. By presenting this case, we aimed to review the treatment and diagnosis, approach to PSTT. A 31-year-old (G2P1A1L1) patient had abnormal vaginal bleeding. Serum ß-HCG was 5.82 mIU/ml and the transvaginal USG detected a polypoid mass in uterine c...
متن کاملPlacental site trophoblastic tumor: a case report.
Patient K.N., age 30, nulliparous deliveries and with one miscarriage, was admitted to the Institute of Gynecology and Obstetrics, Clinical Center of Serbia, in December 2000 with the following diagnosis: Uterine myoma and adnexal mass.
متن کاملPlacental Site Trophoblastic Tumor: Clinical and Pathological Report of Two Cases
Placental site trophoblastic tumor (PSTT) is the rare variant of gestational trophoblastic diseases (GTD), which differs histologically and immunologically from GTD. Diagnosis of PSTT is often difficult and delayed. In most cases, diagnosis is not possible until the surgery is performed. The most therapeutic choice is hysterectomy and it is usually successful. Here we report two cases of PST...
متن کاملExpression of glypican 3 in placental site trophoblastic tumor
BACKGROUND Glypican-3 (GPC3) is a membrane-bound heparan sulfate proteoglycan that functions in embryonic cell growth and differentiation and is highly expressed in the placenta. GPC3 is mutated in Simpson-Golabi-Behmel syndrome, which is characterized by tissue overgrowth and an increased risk of embryonal malignancies. GPC3 has also been implicated in sporadic cancer, particularly hepatocellu...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2007
ISSN: 0893-3952,1530-0285
DOI: 10.1038/modpathol.3800941